Ted Abel

The primary focus of research in the Abel lab is to understand the cellular and molecular mechanisms of long-term memory storage. One of the hallmarks of long-term memory storage is that it requires the synthesis of new genes and new proteins, which act to alter the strength of synaptic connections within appropriate neuronal circuits in the brain. How are the various signals acting on a neuron integrated to give rise to appropriate changes in gene expression? How are changes in gene expression maintained to sustain memories for days, months and even years? What role does sleep play in memory storage? How is learning and memory altered in mouse models of psychiatric and neurodevelopmental disorders?

Sleep and Memory

Molecular Basis of Neurodevelopmental and Psychiatric Disorders




Molecular Basis of
Neurodevelopmental and
Psychiatric Disorders 


Neurobiology of Learning and Memory
Iowa Neuroscience Institute

cAMP Signaling and Hippocampal Function                                                                                                   Behavioral Epigenomics