Junko Kasuya, Ph.D.

Associate Research Sientist
Biography

 

Reduced Function of the Glutathione S-Transferase S1 Suppresses Behavioral Hyperexcitability in Drosophila Expressing Mutant Voltage-Gated Sodium Channels: HL Chen, J Kasuya, P Lansdon, G Kaas, H Tang, M Sodders, T Kitamoto: G3: Genes, Genomes, Genetics 10 (4), 1327-1340, 2020

Milk-whey diet substantially suppresses seizure-like phenotypes of paraShu, a Drosophilavoltage-gated sodium channel mutantJ Kasuya, A Iyengar, HL Chen, P Lansdon, CF Wu, T Kitamoto: Journal of Neurogenetics 33, 164-178, 2019

Lithium-responsive seizure-like hyperexcitability is caused by a mutation in the Drosophila voltage-gated sodium channel gene paralytic:  GA Kaas, J Kasuya, P Lansdon, A Ueda, A Iyengar, CF Wu, T Kitamoto:  Eneuro 3, 2016

Mutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans:  SN Ehaideb, EA Wignall, J Kasuya, WH Evans, A Iyengar, HL Koerselman, AJ Lilienthal, AG Bassuk, T Kitamoto, J R Manak:  Annals of clinical and translational neurology 3, 695-707, 2016

Distinct Modes of Seizure-Like Hyperexcitability as Revealed in Drosophila Sodium Channel Mutants:  A Iyengar, A Ueda, J Kasuya, S Gratz, K O'Connor-Giles, T Kitamoto, CF Wu:  Annals of Neurology 80, S42-S43, 2016

The amnesiac Gene Is Involved in the Regulation of Thermal Nociception in Drosophila melanogaster:  BT Aldrich, J Kasuya, M Faron, H Ishimoto, T Kitamoto:  Journal of neurogenetics 24, 33-41, 2010

A putative amino acid transporter of the solute carrier 6 family is upregulated by lithium and is required for resistance to lithium toxicity in Drosophila:  J Kasuya, GA Kaas, T Kitamoto:  Neuroscience 163, 825-837, 2009

Changes in expression of sensory organ-specific microRNAs in rat dorsal root ganglia in association with mechanical hypersensitivity induced by spinal nerve ligation:  BT Aldrich, EP Frakes, J Kasuya, DL Hammond, T Kitamoto:  Neuroscience 164, 711-723, 2009

Effects of lithium chloride on the gene expression profiles in Drosophila heads;  J Kasuya, G Kaas, T Kitamoto:  Neuroscience research 64, 413-420, 2009

The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females:  T Sakai, J Kasuya, T Kitamoto, T Aigaki:  Genes, Brain and Behavior 8, 546-557, 2009

Neuronal mechanisms of learning and memory revealed by spatial and temporal suppression of neurotransmission using shibirets1, a temperature-sensitive dynamin mutant gene in Drosophila melanogaster :  J Kasuya, H Ishimoto, T Kitamoto:  Frontiers in molecular neuroscience 2, 11, 2009

Characterization of insulin-like growth factor-binding proteins produced by cultured fibroblasts from patients with noninsulin-dependent diabetes mellitus, insulin-dependent …:  S Giannini, S Mohan, J Kasuya, G Galli, CM Rotella, TR Lebon, Y Fujita-Yamaguchi:  Journal of Clinical Endocrinology & Metabolism 92, 623-623, 2007

Cardiac type cGMP-inhibited phosphodiesterase (PDE3A) gene structure: similarity and difference to adipocyte type PDE3B gene:  J Kasuya, SJ Liang, H Goko, SH Park, K Kato, ZD Xu, Steve Hockman, Vincent C Manganiello, Yoko Fujita-Yamaguchi:  Biochemical and Biophysical Research Communications 268 (3), 827-834, 2000

Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels :  V Avdonin, J Kasuya, MA Ciorba, B Kaplan, T Hoshi, L Iverson:  Biophysical Journal 76, A348-A348, 1999

Cyclic nucleotide PDE-3. Quantitation of PDE-3A and -3B mRNAs in rat tissues by RNase protection assay :  T Nagaoka, T Shirakawa, J Kasuya, TW Balon, VC Manganiello, Y Fujita-Yamaguchi:  Cell biochemistry and biophysics 29, 49-66, 1998

Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels:  V Avdonin, J Kasuya, MA Ciorba, B Kaplan, T Hoshi, L Iverson:  Proceedings of the National Academy of Sciences 95, 11703-11708, 1998

Regulation of cAMP phosphodiesterase and DNA synthesis by glucose and insulin in rat vascular smooth muscle cells:  J Kasuya, Y Fujita-Yamaguchi:  Experimental and Clinical Endocrinology & Diabetes 104, 158-159, 1996

Insulin‐like growth factor (IGF) system components in human prostatic cancer cell‐lines: LNCaP, DU145, and PC‐3 cells:  G Kimura, J Kasuya, S Giannini, Y Honda, S Mohan, MH Kawachi, Masato Akimoto, Yoko Fujita‐Yamaguchi :  International Journal of Urology 3 (1), 39-46, 1996

Multiple Transcripts for the Human Cardiac Form of the cGMP-inhibited cAMP Phosphodiesterase:  J Kasuya, H Goko, Y Fujita-Yamaguchi:  Journal of Biological Chemistry 270 (24), 14305-14312, 1995

Multiple Transcripts for the human cardiac type cGMP-Inhibited cyclicAMP Phosphodiesterase (HCGIP2 Type III PDE) :  J Kasuya, H Goko, K Kato, VC Manganiello, Y Fujita-Yamaguchi :  FASEB Journal 9, A1263-A1263 1995

Inhibition of IGF-II-stimulated growth of prostate cancer cells by IGF-I receptor-specific monoclonal antibody and antisense oligonucleotide of IGF-II messenger RNA :  G Kimura, J Kasuya, S Giannini, MH Kawachi, Y Fujita-Yamaguchi, M Akimoto:  J Urol 151, 367, 1994

The purified COOH-terminal domain of the insulin receptor carries activity to stimulate protein kinase activity or autophosphorylation of the β subunit domain of insulin receptor:  J Kasuya, SL Li, S Orr, K Siddle, Y Fujita-Yamaguchi:  Biochemical and biophysical research communications 200, 777-783, 1994

Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification :  J Kasuya, IB Paz, BA Maddux, ID Goldfine, SA Hefta, Y Fujita-Yamaguchi:  Biochemistry 32 (49), 13531-13536, 1993

Molecular and Genomic analyses of human cGMP-inhibited cCMP-Phosphodiesterase (cGI-PDE):  J Kasuya, H Goko, E Meacci, M Taira, V Manganiello, Y Fujita-Yamaguchi:  FASEB Journal 8, A1400-A1400, 1994

Autocrine paracrine roles of insulin-like growth factors in prostate cancer cell growth :  Y Fujita-Yamaguchi J Kasuya, S Giannini, MH Kawachi, G Kimura :  Journal of Cellular Biochemistry, 229-229, 1994

Two new monoclonal antibodies against the α subunit of the human insulin-like growth factor-I receptor :  SL Li, J Kato, IB Paz, J Kasuya, Y Fujita-Yamaguchi :  Biochemical and biophysical research communications 196, 92-98,1993

Growth-stimulatory monoclonal antibodies against human insulin-like growth factor I receptor :  L Xiong, J Kasuya, SL Li, J Kato, Y Fujita-Yamaguchi:  Proceedings of the National Academy of Sciences 89, 5356-5360, 1992

Purification and characterization of guanosine 3', 5'-monophosphate-inhibited low K (m) adenosine 3', 5'-monophosphate phosphodiesterase from human placental cytosolic fractions :  TR LeBon, J Kasuya, RJ Paxton, P Belfrage, S Hockman, VC Manganiello, Y Fujita-Yamaguchi :  Endocrinology 130, 3265-3274, 1992

Purification and characterization of cGMP-inhibited low Km cAMP phosphodiesterase (PDE) from human placental cytosolic fractions:  TR Lebon, J Kasuya, P Belfrage, VC Manganiello, Y Fujita-Yamaguchi:  FASEB Journal 5, A454-A454, 1991

Developmental changes in the expression and distribution of cellular retinoic acid binding protein (CRABP) in the central nervous system of the chick embryo :  T Momoi, T Kitamoto, J Kasuya, H Seno, M Momoi :  Biomedical Research 10, 43-48, 1989

NGF-induced c-Fos gene-expression in human neuro-blastoma cells due to the activation of PI synthesis and C-kinase:  T Momoi, J Kasuya, K Osugi, M Momoi:  Neurochemical Research 13, 283-283, 1988

Activation of CMP-N-acetylneuraminic acid: lactosylceramide sialyltransferase during the differentiation of HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate :  T Momoi, M Shinmoto, J Kasuya, H Senoo, Y Suzuki:  Journal of Biological Chemistry 261 (34), 16270-16273,1986

Changes of phospholipids in human glioma cells by TPA :  M Momoi, J Kasuya, T Momoi :  Neurochemical Research 11, 1754-1754, 1986